Adult PFAPA - a single centre experience

Anti-IL1ß-monoclonal antibody in two adult patients with PFAPA Syndrome - a single centre experience

Background The periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome belongs to the rare nonhereditary autoinflammatory diseases and normally onsetting in childhood, but despite of tonsillectomy persisting or newly occurring in adulthood. The exact pathogenesis is not clear, but to our understanding it is an acquired autoinflammatory disease due to an unregulat...

PFAPA syndrome in the Czech Republic: a single-centre experience

Purpose PFAPA syndrome (Periodic Fever, Aphthous stomatitis, Pharyngitis and Adenitis) is an idiopathic autoinflammatory disease with the first manifestation before 5 years of age. Fever attacks lasting for 3-6 days have individual periodicity within about 3-8 week intervals. They are accompanied by individual combination of other symptoms among which culture-negative pharyngitis/tonsillitis, o...

Periodic Fever accompanied by Aphthous stomatitis, Pharyngitis, and cervical Adenitis syndrome (PFAPA syndrome) in adults

BACKGROUND The new syndrome, known as PFAPA, of periodic fever characterized by abrupt onset of fever, malaise, aphthous stomatitis, tonsillitis, pharyngitis and cervical adenopathy has been described only in pediatric patients. It usually begins before the age of 5 years and in most cases resolves spontaneously before age 10. OBJECTIVES To describe a series of adults with PFAPA syndrome. M...

Re-organising Junior Doctors During the COVID-19 Outbreak: A Single Centre Experience in the United Kingdom

A case of adult‐onset periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome in Japan

Adult-onset periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome is rare. We report the case of a 23-year-old woman with PFAPA syndrome in Japan. Her symptoms lasted for approximately 5 days in each period regardless of nonsteroidal anti-inflammatory drug or antibiotic treatment. She was diagnosed with PFAPA syndrome based on her periodic self-limiting symptoms and no...

Management of Perinatal Testicular Torsion: A Single Centre Experience

Perinatal testicular torsion (PTT) is a rare entity. The management of PTT is controversial, due to the low viability of the testis and the possibility of bilateral torsion. This is a review of our experience with six cases of PTT, highlighting diagnostic and therapeutic difficulties of this condition.